To be honest, I don't remember reading in the books about Rosalie having a mole...
I think in all honesty it's a small movie mistake...
I don't know if Nikki has that mole or not but it could be considered as a beauty spot. I remember a lot of beautiful actresses faked that spot... I'm sure that the production team let it be there because it is considered a symbole of beauty.
For the science, in general, moles are a few cells in which a lot of pigment is stored, we know that Laurant didn't loose the dark teint of his skin during transformation so I think that pigment stayed where it is. So, if you look it from that way I think vampires can have moles.
Though if you look at wart like moles, the once that are bad, first signs of skin cancer and all I think the vemon corrects that.




